Bioperine is an extract from the fruit of Piper nigrum L (black pepper) or Piper longum L (long pepper) that contains 95 percent of piperine. Black pepper is a common household spice. Extract from black pepper has also been used extensively as a medicine. To reach the greatest quality during the harvest, the pepper is reaped before ripening and after that is placed to dry under the sun rays. Bioperine is known for its effect to enhance the efficiency of many supplement nutrients. Bioperine acts to enhance the body’s natural therogenic activity – giving the name thermonutrient. This enhancement brings about increased metabolic rate creating demand for supple of many nutrients such as vitamins, minerals, herbals, amino acids. It sets in motion a process that brings about better digestion and faster gastrointestinal absorption.

Dicaffeine Malate is actually a combination of caffeine and malic acid. Malic acid in turn is won out of Apple Juice and is a food additive with the E number E296. In green apples, the sour taste is due to malic acid. When cocaine was outlawed, The Coca-Cola Company introduced dicaffeine malate as the replacement. It is a stimulant, much like caffeine, but apparently gentler on the digestive tract. Many traits associated with regular caffeine are found in this caffeine salt, but through the interaction with malic acid, additional features have been observed. Dicaffeine malate is a very common ingredient in dietary supplements, it is supposed to optimize energy levels, increase mental focus and cognitive awareness, but also is able to stimulate thermogenesis.

Evodiamine, an alkaloid extract from the Evodiae Fructus plant is known as Evodiamine. It has been referred to as a “hot nature” herb in Chinese literature and medicine. Based on animal studies, Evodiamine increases the natural fat burning rate and stimulates vanilloids for reduction of fat intake. It increases body temperature, influences the adrenal glands to secrete catecholamines and also affects the metabolism of certain drugs. Since it acts like a thermogenic and increases the overall temperature, more fat and calories are burnt due to its intake. This alkaloidal compound has anti obesity effects due to UCP1 (uncoupling protein 1) thermogenesis. In part, evodiamine can prevent diet induced obesity from developing further. It is available in the form of supplement or through Evodiae Fructus plant.

Forslean

Fucoxanthin is the new dietary supplement which is growing in demand with every passing day. It is a carotenoid found in edible brown and red seweed like hijiki (Hijikia Fusiformis) and wakame (undaria pinnatifida). Fucoxanthin helps the process of weight loss and burning of fat. Also available as a nutritional supplement, Fucoxanthin has been explored by experts for weight loss. Based on research it has been found out that Fucoxanthin tends to target UCP1 protein for increasing the rate of abdominal fat burning. It also helps in the stimulation of DHA production which thereby results in reduction of bad cholesterol, increases insulin sensitivity and improves triglycerides. Fucoxanthin also affects your body’s ability to process energy, which means that while unhealthy fat is being burnt you can maintain a high energy level.

Guggulsterone- Commiphora wightii, or the so called Guggul tree is a flowering shrub or rather a small tree which can grow up to a size of 4 meters. Once very common in India, it is now there listed as endangered, but not in northern Africa or elsewhere in central Asia. It was very popular in the Indian Ayurvedic medicine, but also currently in the western medicine for treating of heart problems. The hydrocarbon secretion of Guggul contains a plant sterol, guggulsterone, which in the human body seems to act as an antagonist to the farnesoid X receptor. Furthermore, guggulsterone is active in increasing the natural thyroid production. This in turn stimulates the metabolism and may raise the body temperature, burning stored excess fat.

Razberi-K

Sclareolide, which is thought to increase cAMP (cyclic adenosine monophosphate) levels in the body through the stimulation of the "adenylate cyclase" (AC) enzyme. This stimulation is believed to help activate increased fat burning.