Caffeine is the most widely used legal stimulant of the central nervous system and is also used in D4 Extreme Weight Loss, with characteristics that have been described as restoration of alertness and removing from drowsiness. Coffee, Tea, many soft drinks and energy drinks as well as nutrition supplements have this ingredient, which is a psychoactive substance, a xanthine alkaloid that can act as a adenosine receptor antagonist, as well as a phosphodiesterase inhibitor. Although regular use of caffeine seems to have nootropic effects, enhancing cognitive abilities, it also is known to provide long term effects on the nervous and cardiovascular system, like in one study it was proven that people with normal to low blood pressure have the possibility of developing a heart disease significantly reduced, as well as the chance of getting the Parkinson’s disease.

Clary Sage Powder

Evodia Rutaecarpa contains the extracts of the plant Tetradium, which is a genus in the family Rutaceae, also known as the Bee bee tree, or Evodia. This extracts contain a chemical which is called evodiamine, which seems to influence the uncoupling protein 1, also called thermogenin, which is involved in the process allowing energy to be burned as heat. Evodiamine is actually a bioactive alkaloid, used by the traditional Chinese medicine for ages under the name Wu Chu Yu in connection with weight control and fat burning solutions for overweight to obese people. Evodiamine seems to interact with vanilloids, with the effect that the uptake of fat is lowered, but at the same time the fat burning rate is increased, resulting in actual weight loss.

Octopamine is related to noradrenaline. Octopamine was discovered by Vittorio Erspamer, an Italian scientist in 1948. Octopamine has a significant role in mollusks and is the central nervous system in snail. Octopamine also has a vital role in memory and learning in the fruit fly and honey bee. Octopamine is also useful for the firefly in releasing the light production. Octopamine mobilizes releasing fat in mammals and this has developed into promotion as a slimming aid on the internet. However, there is no apparent evidence about Octopamine facilitating weight loss. Octopamine also significantly increases the blood pressure in combination with stimulants such as weight loss supplements. This is extensively used in energy demanding insects such as spiders, lobsters, crabs and crayfish as their behaviors also include egg-laying, jumping and flying. Among vertebrates, Octopamine substitutes norepinephrine and as well exhibits common side effects. Octopamine is sited in the locust jump such that it modulates the muscle activity allowing the leg muscles to contract effectively.

Passion Flower- Passion vines, or Passiflora, are a 500 species strong genus of flowering plants that all belong to the family of Passifloraceae. While most of the plants are classified as vines, there are also some shrubs and herbaceous plants that can be found. With the exception of Europe and Africa, as well as Antarctica, these plants are found all over the rest of the world. While the passion flower is mostly known for the Maracuja, or Passiflora edulis, the passion fruit, the vines of some species in this genus are known to have properties that have been used by Native Americans for treatment of insomnia, epilepsy and hysteria, as noted with Passiflora incarnata. Many other species contain beta carboline harmala alkaloids, which function as monoamine oxidase inhibitors and are powerful antidepressants.

White Willow Bark, or Salix alba, is a willow commonly found in Europe and adjacent parts of western and central Asia. The bark of the White Willow has been used for centuries against fevers and to ease pains and aches. Already Hippocrates wrote about the White Willow bark powder two thousand five hundred years ago. The active ingredient of the White Willow bark is called salicin, a relative to aspirin and chemical derivative of the salicylic acid. When ingested, salicin is converted to salicylic acid, a beta hydroxy acid. As a nutritional supplement, White Willow products are being propagated as weight loss additives, whereby the scientific community has yet to provide any corroboration to this allegation. Besides the well known anti inflammatory characteristics, any other uses have not been approved by the FDA.