HMB or beta-Hydroxy beta-methylbutyric acid is a leucine metabolite, synthesized in the human body. Dr. Steve Nissen discovered this metabolite in scientific studies for decreasing breakdown of muscles and increasing the muscles mass. In the last few years, HMB has gained tremendous popularity as a supplement for bodybuilders. They use it for hypertrophy gains and ergogenic effects like anabolic, lipolytic and anti-catabolic effects. This supplement is not only safe to use but it also helps in controlling the total cholesterol level in the human body. It can make an individual more muscular, reduce breakdown of muscles and burn fat. HMB tends to speed up the process of fat oxidation by the synthesis of oxidative organelles like mitochondria. It is also helps in enhancing the function of immune system and when supplemented with L-carnitine, creatine monohydrate and protein, it can be very effective.