Chromium Polynicotinate, which is a form of chromium, an essential trace mineral that is needed for the body's production of insulin. Insulin is a hormone that stabilizes the body's blood sugar level.

Garcinia Cambogia, native to Southeast Asia, is a tropical fruit which belongs to the citrus family. This Indian and African fruit is extremely popular for its extract hydroxycitric acid. Without suppressing your appetite or stimulating the brain, this acid acts as an effective weight loss supplement. It not only provides the required energy but also improves the signaling system of the body. When the signaling system gets better, the brain is informed by the body that it is full. This system is not very active in obese people, which is why they eat a lot. Garnicia Cambogia extract of hydroxycitric acid is more effectual when used with chromium. The intake of chromium in western countries is very low, due to which people become diabetic or obese.

Guarana has in recent times received widespread popularity because of an energy drink. It is actually a climbing plant in the family related to maple and is native to the Amazon region, predominantly in Brazil. It is a flowering plant with big leaves, but the fruit is the most prominent component, not bigger than a coffee bean. Guarana fruit has about the double content of caffeine when compared to the coffee bean. Besides the cognitive and fatigue reducing effects of caffeine, guarana displays also other interesting properties, such as the assistance in a weight loss program; namely, guarana affects the perception of the satiation, making the person feel full sooner. Further antioxidant and antibacterial effects have been noted as well. In combination with linoleic acid, guarana has shown fat cell reduction effects in mice.

Hoodia Gordonii derives from a leafy plant and is utilized to suppress ones appetite.

Synthetic Guggulsterones are derived from a herb, commiphora mukul, which has been proven to restore lagging metabolic rate brought about by dietary caloric deficiency, such as a diet low in carbohydrates. Though it has cholesterol lowering ability, it is also known as powerful weight loss agent due to the increased conversion of the inactive thyroid hormone T4 into its active part T3 in the liver. Furthermore, Guggulsterones are also known to stimulate the thyroid directly by enhancing TSH (Thyroid Stimulating Hormone) production. This is especially true for two specific guggulsterones codenamed Z and E.