Synephrine, a semi-selective sympathomimetic, is used to stimulate the adrenaline system. Also known as ‘zhi shi’, green orange or bitter orange; it is a chief, active constituent found in the fruit belonging to the plant, Citrus aurantium. Synephrine is not only similar to ephedra in its chemical composition but also serves the same benefits as caffeine or ephedrine. However, it mildly stimulates the fat metabolism without causing any of the side effects associated with ephedra based products. The best advantage of using Synephrine is that it increases the metabolic rate without affecting the hemodynamics. Thus, it is comparatively much safer than ephedra. Since Synephrine promotes weight loss and supports thermogenesis, Synephrine supplements are an ideal solution for dieters and weight watchers. The total intake should be between 2 to 10 mg. per day.