Capsaicin is used in several skin preparations and is used to relieve pain. It is available in the market in various forms such as ointments, creams, gels, liquids, lotions, sticks and pads under marketing names such as Capsagel, Zostrix, Arthricare for Women and Icy Hot Arthritis Treatment. A very astonishing fact is that capsaicin happens to be the active part of chili peppers. Though it is an irritant producing burning sensation on any tissue that comes in contact with it, it depletes substance P. Substance P transmits impulses of pan to the brain. It relieves pain due to diseases such as osteoarthritis, diabetes neuropathy and rheumatic arthritis. Capsaicin has not had any drug interactions till date. But this does not means that it can never have any interaction with any other drug. It is always best to confirm with your doctor if you really need to use capsaicin. Also, it is best to use this drug only in specified quantities.

Guarana is a South American climbing plant belonging to the genus of trees and shrubs called Maple. This plant is common around the Amazon and very present in Brazil. The fruit of the guarana plant is being used in that country to produce a diversity of soft drinks and beverages, having the double caffeine content of the coffee bean. Other nutrients that are contained in the seed besides caffeine are protein, fat and starch, but also adenine, choline, guanine, resin, tannin and xanthine, just to name a few. The cognitive effects of guarana are well documented, but the appetite suppressant qualities of guarana are relatively new. A study has proven that a combination of yerba mate, guarana and damiana leads to a tenfold weight loss quantity when compared with a placebo.

Kola Nut has a euphoric and stimulating effect on the heart and central nervous system and produces a heightened state of euphoria and well-being.

Yerba Matte- Described as an ancient drink of friendship derived from a small shrub. It is sometimes spelled as yerba mate and people drink it in order to gain energy producing properties without consuming caffeine as they would in normal tea or coffee. People believe that yerba mate is a appetite suppressant, clears the mind as well as relieving allergies, improving sleep patterns and lifting the mood, that is why it is used in Yellow Hornet . It is advertised as an aid to weight loss, a fortifier of the immune system, a colon cleanser and even as a means of extending life. It is prepared as an infusion, with twigs and leaves immersed in boiling water in order to produce a tisane. Traditionally it is made in a vessel which is then shared among friends.

Yohimbe- Basically a tree bark, Yohimbe is rich in pharmacologically active chemicals. It is commonly found in products developed for body building and enhancing male performance. The use of Yohimbe causes serious side effects too that include renal failure, seizures and in very rare cases, even death. Individuals suffering from low blood pressure, heart disease, liver or kidney disease, and diabetes should refrain from using any kind of Yohimbe supplements. Taking larger doses of Yohimbe can cause weakness, stomach disorders, fatigue, and nervous stimulation followed by paralysis. It is therefore important to avoid self-medication. Sometimes, side effects may arise even if small amounts of this supplement are taken, especially for prolonged periods. If you are already taking drugs for treating some health condition, it is best to avoid this supplement.